VHL protein

The VHL protein is a key regulator in our bodies that helps control cell growth and blood vessel formation. It acts as a quality control agent by identifying and marking abnormal proteins or low oxygen conditions, directing their destruction. This process prevents uncontrolled cell growth, which could lead to tumors. When the VHL gene, which produces this protein, is defective or missing, it can result in excessive blood vessel growth and tumor development, as seen in conditions like von Hippel-Lindau disease. Overall, VHL maintains cellular balance and prevents abnormal growth by regulating important cellular pathways.