vascular remodeling in ischemia

Vascular remodeling in ischemia refers to the process where blood vessels change structure in response to reduced blood flow. When tissues don't receive enough oxygen and nutrients due to blocked or narrowed arteries, the body tries to adapt by forming new blood vessels or altering existing ones to improve blood supply. This involves growing new vessels (angiogenesis), expanding or contracting vessel walls, and reorganizing tissue structure around the vessels. These changes aim to restore adequate blood flow, support tissue survival, and repair damage caused by ischemia.