Variant classification

Variant classification is the process of assessing a specific genetic change, called a variant, to determine its significance for health. Scientists analyze data about the variant's pattern, how it affects genes, and its association with diseases. Based on this, variants are categorized into groups such as benign (not harmful), likely benign, uncertain significance, likely pathogenic, or pathogenic (causing or increasing disease risk). This classification helps healthcare providers and individuals understand potential health implications, guiding medical decisions and personalized care.