UGT1A1

UGT1A1 is a gene that produces an enzyme responsible for helping your body process and remove certain substances, including bilirubin— a yellow compound formed when your body breaks down red blood cells. Proper functioning of UGT1A1 ensures bilirubin levels stay normal, preventing jaundice and other health issues. Variations in this gene can affect enzyme activity, influencing how efficiently your body clears bilirubin, which can impact your risk for conditions like Gilbert's syndrome or affect how you respond to certain medications like irinotecan used in cancer treatment.