Ubiquitin ligases

Ubiquitin ligases are specialized enzymes that tag unwanted or damaged proteins with a small molecule called ubiquitin. This tagging process signals the cell's machinery to degrade and remove the tagged proteins, helping maintain cellular health and balance. By controlling the degradation of specific proteins, ubiquitin ligases play a critical role in regulating various biological processes, including cell cycle, DNA repair, and immune responses. Their precise activity ensures that cellular functions proceed correctly and that damaged or excess proteins do not accumulate, preventing potential diseases.