U.S. Route 421

U.S. Route 421 is a north-south highway that stretches approximately 400 miles, running through the eastern United States. It begins in the city of Fort Fisher, North Carolina, and extends northward to the city of Michigan City, Indiana. The route connects several states, including North Carolina, Virginia, Kentucky, and Indiana, serving as an important corridor for regional travel and commerce. Along the way, it passes through diverse landscapes, towns, and cities, providing access to local roads, highways, and attractions. U.S. Route 421 is part of the Federal Highway System, facilitating efficient transportation across the eastern U.S.