Tumor necrosis factor inhibitors (TNFi)

Tumor necrosis factor inhibitors (TNFi) are medications that block a substance called tumor necrosis factor-alpha (TNF-alpha), which plays a key role in causing inflammation and immune responses. In certain conditions like rheumatoid arthritis and Crohn’s disease, this inflammation damages tissues and joints. TNFi drugs help reduce this harmful inflammation, alleviating symptoms and preventing tissue damage. They are usually given via injections or infusions and are prescribed under medical supervision to balance their benefits against potential side effects. Overall, TNFi medications are important tools in managing chronic inflammatory diseases by targeting specific parts of the immune system.