Tumor Necrosis Factor-alpha

Tumor Necrosis Factor-alpha (TNF-alpha) is a protein produced by the body's immune cells to help fight infections and manage inflammation. It plays a key role in signaling the immune system to respond to harmful threats, such as bacteria or viruses. However, when produced in excess or improperly regulated, TNF-alpha can contribute to chronic inflammation and various autoimmune conditions, where the immune system attacks the body's own tissues. Medications targeting TNF-alpha are used to treat diseases like rheumatoid arthritis and Crohn's disease by reducing excessive inflammation.