TUBA (Alpha-tubulin)

TUBA, which encodes alpha-tubulin, is a gene that provides instructions for making a protein essential for forming microtubules—tiny, tube-like structures inside cells. Microtubules are part of the cell’s skeleton, helping maintain its shape, assist in cell division, and transport materials within the cell. Alpha-tubulin works together with beta-tubulin to build these microtubules. Proper function of TUBA is crucial for healthy cell activity. Mutations or defects in this gene can disrupt microtubule formation, potentially leading to developmental issues or disease.