TSC1 (tuberous sclerosis complex 1)

TSC1 is a gene that produces a protein called hamartin, which plays a key role in controlling cell growth and division. It helps regulate pathways that prevent cells from growing too quickly or abnormally. When TSC1 is mutated or faulty, this regulation is disrupted, leading to the development of benign tumors called hamartomas in various organs. These growths are characteristic of tuberous sclerosis complex (TSC), a genetic disorder that can cause skin issues, seizures, and other health problems. Essentially, TSC1 helps keep cell growth in check, and its malfunction can contribute to disease development.