Tropomyosin receptor kinase

Tropomyosin receptor kinases (Trk) are proteins found on nerve cells that act as receptors for specific growth factors called neurotrophins. When these neurotrophins bind to Trk, they activate the receptor's internal signals, promoting nerve cell survival, growth, and function. This process is essential for healthy nervous system development and maintenance. Mutations or dysfunctions in Trk receptors can be linked to neurological diseases and certain types of cancer, making them important targets for medical research and treatment.