TrkB

TrkB is a protein found on the surface of nerve cells that acts like a receiver for certain growth factors, mainly brain-derived neurotrophic factor (BDNF). When BDNF binds to TrkB, it activates the receptor, prompting the nerve cell to grow, survive, and form connections—processes essential for learning, memory, and brain health. TrkB signaling helps maintain healthy brain function, and disruptions in this pathway have been linked to neurodegenerative and mood disorders. Overall, TrkB plays a critical role in supporting the health and adaptability of the nervous system.