Image for tricyclic antidepressants (TCAs)

tricyclic antidepressants (TCAs)

Tricyclic antidepressants (TCAs) are a class of medications used to treat depression and certain anxiety disorders. They work by increasing the levels of neurotransmitters, like serotonin and norepinephrine, in the brain, which help improve mood and emotional balance. Developed in the 1950s, TCAs are effective but can have side effects such as weight gain, drowsiness, and dry mouth. They are often used when newer antidepressants, like SSRIs, aren't effective or suitable. Due to potential side effects and interactions, these medications should be prescribed and monitored by a healthcare professional.