Treatment Resistant Depression (TRD)

Treatment-resistant depression (TRD) refers to a form of depression that does not improve after trying at least two different antidepressant medications at adequate doses and durations. It indicates that standard treatments haven't been effective in relieving symptoms. TRD can be challenging to manage and may require alternative therapies, such as psychotherapy, brain stimulation techniques, or combination treatments. Understanding TRD helps clinicians tailor more personalized and effective approaches to help individuals regain stability and improve their quality of life.