transfusion-associated immunomodulation

Transfusion-associated immunomodulation (TAIM) refers to the immune system changes that can occur after receiving a blood transfusion. When blood or blood components are transfused, it can relax or suppress certain parts of the immune response. This suppression might reduce the body's ability to fight infections or increase the risk of developing certain immune-related complications, such as recurrent infections or cancer recurrence. TAIM is thought to happen because the transfused blood contains immune cells and substances that influence the recipient’s immune system, leading to these subtle but significant immune adjustments.