
Total synthesis of strychnine
Total synthesis of strychnine involves constructing this complex natural molecule from simpler starting materials through a series of carefully planned chemical reactions. Chemists design a step-by-step pathway that builds the molecule’s intricate structure, including multiple rings and stereocenters, in a controlled manner. This process requires precise control over reaction conditions to ensure the correct arrangement of atoms and spatial configuration. Achieving this synthesis demonstrates mastery over organic chemistry and provides insights into the molecule’s architecture, enabling applications in medicine and advancing synthetic methodologies.