Topoisomerases

Topoisomerases are essential enzymes in cells that manage DNA’s structure during processes like copying or dividing. DNA is a long, thread-like molecule that can become tangled or overly coiled. Topoisomerases cut the DNA strands to relieve these tangles, allowing the DNA to untangle or relax, then reseal the breaks. This activity prevents damage and ensures accurate DNA replication and cell division. They act like molecular “wrenches” or “twisters,” maintaining the proper shape of DNA so the cell can function smoothly. Topoisomerases are crucial for genetic stability and cell health.