Tolerance and withdrawal

Tolerance occurs when the body becomes accustomed to a substance, requiring higher doses to achieve the same effect. Withdrawal happens when someone stops using that substance after dependency has formed, leading to physical and psychological symptoms like anxiety, sweating, or nausea. Essentially, tolerance means needing more of a substance over time, while withdrawal represents the discomfort experienced when stopping use. Both are signs of the body's adaptation to ongoing substance exposure and indicate potential dependence.