TNF Receptor 1 (TNFR1)

TNF Receptor 1 (TNFR1) is a protein found on the surface of many cell types. It acts as a receiver for a molecule called tumor necrosis factor alpha (TNF-α), which is involved in inflammation and immune responses. When TNF-α binds to TNFR1, it triggers a series of signals inside the cell that can lead to inflammation, cell survival, or programmed cell death (apoptosis). TNFR1 plays a crucial role in controlling immune responses and inflammation, and its regulation is important for preventing excessive tissue damage or chronic inflammatory diseases.