Image for TNF-alpha (Tumor Necrosis Factor-alpha)

TNF-alpha (Tumor Necrosis Factor-alpha)

TNF-alpha (Tumor Necrosis Factor-alpha) is a protein produced by immune cells that plays a key role in inflammation and the body's response to infection or injury. It helps coordinate the immune system’s attack on harmful agents, such as bacteria or viruses, by signaling other immune cells. However, when produced in excess or inappropriately, TNF-alpha can contribute to chronic inflammation and tissue damage, which are involved in conditions like rheumatoid arthritis, inflammatory bowel disease, and psoriasis. It is an important target for certain medical treatments aimed at reducing excessive inflammation in these diseases.