Image for tissue plasminogen activator

tissue plasminogen activator

Tissue plasminogen activator (tPA) is a medication used to dissolve blood clots. It works by activating an enzyme that breaks down fibrin, the net-like protein that holds clots together. This helps restore blood flow in cases like strokes caused by clots blocking arteries or certain heart attacks. tPA is most effective when given quickly after symptom onset. While it can be life-saving, it also increases the risk of bleeding, so it must be administered carefully under medical supervision. Overall, tPA is a critical tool in managing acute clot-related conditions.