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tight junctions

Tight junctions are specialized connections between neighboring cells that form a selective barrier, preventing unwanted substances from slipping between the cells. Found mainly in tissues like the skin and lining of organs, they help maintain the integrity and compartmentalization of different body areas. By sealing the spaces between cells, tight junctions regulate what passes through the cell layer, ensuring essential nutrients get in while harmful substances stay out. They are vital for tissue function, protection, and maintaining proper internal environments in the body.