Thyroid-stimulating hormone receptor

The thyroid-stimulating hormone receptor (TSHR) is a protein located on the surface of thyroid gland cells. It detects the hormone TSH, which is produced by the pituitary gland, and responds by activating the thyroid gland to produce hormones that regulate metabolism, energy, and growth. TSHR acts like a key that unlocks the thyroid’s activity when TSH binds to it. Proper function of TSHR is essential for maintaining balanced thyroid hormone levels. Problems with this receptor, such as mutations or autoantibodies, can lead to thyroid disorders like hyperthyroidism or hypothyroidism.