Thyroid peroxidase (TPO) antibodies

Thyroid peroxidase (TPO) antibodies are immune system proteins that mistakenly attack the thyroid gland, specifically targeting an enzyme called thyroid peroxidase essential for hormone production. Their presence indicates an autoimmune response, commonly seen in conditions like Hashimoto's thyroiditis or Graves' disease. Elevated TPO antibodies can lead to thyroid dysfunction, often resulting in hypothyroidism (low hormone levels). Testing for these antibodies helps diagnose autoimmune thyroid diseases, guiding appropriate treatment. In summary, TPO antibodies are markers showing the immune system is attacking the thyroid, which can impact your thyroid health and hormone balance.