Thorough QT Study Guidelines

Thorough QT (TQT) Study Guidelines are protocols used in clinical research to assess whether a new medication affects the heart's electrical activity, specifically the QT interval on an electrocardiogram (ECG). Prolongation of this interval can indicate a risk of dangerous irregular heartbeats. These guidelines ensure that the study is well-designed, controlled, and reliable, helping regulators determine if the drug is safe regarding its potential to cause cardiac rhythm issues. Essentially, they provide a standardized approach to evaluate and minimize the heart-related risks associated with new drugs before approval.