The Mullis effect

The Mullis effect refers to the phenomenon where the presence of a small, specific genetic sequence, like a target DNA segment, can be amplified exponentially in a laboratory setting using PCR (Polymerase Chain Reaction). This process allows scientists to detect and analyze tiny amounts of genetic material by repeatedly doubling the amount of the target DNA through cycles of heating and cooling. The effect demonstrates how relatively minute initial samples can become large enough to study, enabling breakthroughs in genetics, forensics, and medicine by making minimal genetic evidence or data accessible for detailed examination.