
The kinase hypothesis
The kinase hypothesis suggests that kinases are enzymes that transfer phosphate groups to other proteins, acting as switches to turn these proteins on or off. This process, called phosphorylation, regulates many cellular functions, such as growth, division, and communication within the cell. In diseases like cancer, abnormal kinase activity can lead to uncontrolled cell growth. Understanding this hypothesis helps scientists develop targeted treatments, such as kinase inhibitors, to block harmful kinase activity and restore normal cellular function.