"The Amyloid Hypothesis of Alzheimer's Disease"

The Amyloid Hypothesis of Alzheimer's Disease suggests that the buildup of a protein called beta-amyloid in the brain is a primary cause of the disease. This protein accumulates into sticky plaques, which disrupt normal brain cell communication and trigger inflammation and cell death. These changes lead to the memory loss, confusion, and other cognitive problems characteristic of Alzheimer's. The hypothesis drives research aiming to reduce or prevent amyloid buildup, hoping to slow or stop disease progression. While widely supported, the exact relationship between amyloid and Alzheimer's remains under ongoing investigation.