The Amyloid Hypothesis

The Amyloid Hypothesis suggests that the buildup of amyloid-beta protein plaques in the brain is a primary cause of Alzheimer’s disease. These sticky plaques form outside neurons and disrupt communication between brain cells, leading to cognitive decline. The hypothesis proposes that clearing or preventing amyloid plaque formation could slow or stop the progression of Alzheimer’s. While supported by many studies, this idea is still under investigation, as some treatments targeting amyloid have not yet produced significant clinical benefits. Nonetheless, understanding amyloid plaques remains a key focus in Alzheimer’s research.