Th21/Th2 paradigm

The Th21/Th2 paradigm refers to two types of immune responses driven by T-helper cells, which are crucial for fighting infections. Th1 cells focus on fighting intracellular pathogens like viruses and certain bacteria, activating immune responses that target these invaders. In contrast, Th2 cells help combat extracellular threats, such as parasites and allergens, by promoting antibody production and influencing other immune cells. This balance between Th1 and Th2 responses is important for maintaining overall immune health and can influence conditions like allergies, asthma, and autoimmune diseases, highlighting how the immune system adapts to different challenges.