Tamm-Horsfall protein

Tamm-Horsfall protein, also known as uromodulin, is a protein produced by cells in the kidneys' tubules. It is the most abundant protein in healthy urine and plays a role in protecting the urinary tract. It helps prevent bacteria and crystals from sticking to the urinary walls, reducing infections and kidney stone formation. Additionally, Tamm-Horsfall protein may influence immune responses and kidney function. Its proper production and function are important for maintaining urinary health, and abnormal levels can be associated with certain kidney diseases.