T follicular helper cell

T follicular helper (Tfh) cells are a specialized type of immune cell that help B cells create antibodies, which are proteins that recognize and fight specific germs like bacteria and viruses. They reside mainly in the lymph nodes and the spleen, where they interact closely with B cells, providing signals that guide their development into cells that produce high-quality, targeted antibodies. Tfh cells are essential for effective long-term immunity, as they promote the production of memory B cells and robust antibody responses after infection or vaccination.