Image for systemic sclerosis (scleroderma)

systemic sclerosis (scleroderma)

Systemic sclerosis, or scleroderma, is a chronic autoimmune disease where the immune system mistakenly attacks the body's tissues, causing thickening and hardening of the skin and internal organs. This occurs because excess collagen, a protein that provides structure, is produced, leading to fibrosis or scarring. Symptoms vary but can include skin tightening, joint pain, and problems with the lungs, heart, or kidneys. The exact cause is unknown, and it can range from mild to severe. While there's no cure, treatments aim to manage symptoms and prevent organ damage.