Steere's cohort study

Steere's cohort study investigated whether Lyme disease in mice could be transmitted to uninfected mice through tick bites. Researchers infected some mice with the bacteria that cause Lyme disease and allowed ticks to feed on them. These ticks then fed on healthy mice. Over time, they observed that the previously healthy mice became infected after being bitten by infected ticks, demonstrating that ticks can transmit Lyme disease bacteria from one host to another. This study provided key evidence confirming ticks as the primary vectors of Lyme disease transmission.