STAR*D Trial

The STAR*D trial was a large study designed to find the most effective treatments for depression. Participants with depression went through multiple steps of medication, with the goal of achieving remission. If one medication didn't work, they switched or added others, trying different options. The study helped show that depression often requires multiple treatment attempts and that personalizing care can improve outcomes. It provided valuable insights into how depression can be treated more effectively by understanding that it may take several tries to find the right approach.