SSH (Suppression Subtractive Hybridization)

Suppression Subtractive Hybridization (SSH) is a laboratory technique used to compare two sets of genetic material, such as cells before and after a treatment. It identifies specific genes that are active in one sample but not the other. The method involves hybridizing (pairing) similar genetic sequences from both samples, then selectively amplifying the unique ones. This process helps researchers discover new genes or understand how cells respond to different conditions, making SSH valuable in genomics and disease research.