SQSTM1

SQSTM1, also known as p62, is a protein that plays a crucial role in cell health by helping to remove damaged or unnecessary proteins through a process called autophagy, essentially cellular cleaning. It acts as a sensor and adaptor, guiding waste proteins to the cell's disposal system. SQSTM1 also participates in regulating inflammation and cell survival. Mutations or dysfunctions in SQSTM1 are linked to various diseases, including some neurodegenerative disorders and certain types of cancer. Overall, SQSTM1 is vital for maintaining cellular balance and preventing the buildup of harmful materials.