Spatial Genome Organization

Spatial genome organization refers to how our DNA is arranged inside the cell nucleus. Instead of being randomly spread out, the DNA folds and positions itself purposefully, bringing certain genes and regions closer together or farther apart. This arrangement influences gene activity, turning genes on or off depending on their location. The organization helps cells efficiently manage gene expression, DNA repair, and other essential processes. Understanding this spatial layout provides insight into how our genetic information functions and how its misorganization may lead to diseases.