Solid-phase Red Cell Adherence Technique (SPRCA)

The Solid-phase Red Cell Adherence Technique (SPRCA) is a laboratory method used primarily in blood typing and screening for antibodies. In this technique, red blood cells are attached to a solid surface, allowing scientists to mix them with serum samples from patients. If antibodies are present in the serum, they will bind to the red blood cells, causing visible cell adherence. This helps identify blood group compatibility and detect potential transfusion reactions. SPRCA is a valuable tool in ensuring safe blood transfusions and managing blood compatibility issues in medical settings.