SMA Type I

Spinal Muscular Atrophy (SMA) Type I is a genetic condition that causes a significant loss of nerve cells responsible for controlling muscle movements. This leads to severe muscle weakness and difficulty with everyday activities like sitting up, swallowing, and breathing, usually appearing within the first six months of life. Babies with SMA Type I often have low muscle tone and may require life-supporting interventions. It is caused by a mutation in the SMN1 gene, which is crucial for nerve and muscle health. Early diagnosis and treatment can improve quality of life and outcomes.