single-molecule localization microscopy (SMLM)

Single-molecule localization microscopy (SMLM) is a powerful imaging technique used in biology to visualize tiny structures at a molecular level. It works by taking many images of fluorescently labeled molecules that glow only briefly. By precisely determining the location of each glowing molecule over time, SMLM can create a detailed, high-resolution image of cellular components. This allows scientists to study complex cellular processes and interactions in great detail, revealing insights that traditional microscopy might miss. SMLM is especially valuable for research in areas like neuroscience and cancer biology, where understanding molecular interactions is crucial.