Single-chain variable fragments (scFv)

Single-chain variable fragments (scFv) are engineered antibody components used in medicine and research. They consist of the two key regions of an antibody—called variable regions—that recognize specific targets like bacteria or viruses. These regions are connected by a short flexible linker, creating a compact, single-chain molecule. ScFvs retain the ability to bind precisely to their target but are smaller and easier to produce than full antibodies. This makes them useful for targeted therapies, diagnostics, and research applications, as they can quickly and effectively seek out specific molecules in the body.