Sigma-1 Receptor

The Sigma-1 receptor is a protein mainly found in the brain that helps regulate cell activity and protect neurons. It acts like a molecular chaperone, assisting other proteins to function properly, especially during stress or injury. The receptor influences mood, cognition, and pain perception, and is involved in the effects of certain drugs, including those used for mental health and neurological conditions. By modulating how cells respond to signals and stress, the Sigma-1 receptor plays a crucial role in maintaining balanced brain function and potentially offers targets for new therapies.