shotgun proteomics

Shotgun proteomics is a technique used by scientists to identify and analyze all the proteins in a complex biological sample, like blood or tissue. It works by breaking down the proteins into smaller pieces called peptides, then using advanced instruments to measure their properties. A computer then matches these measurements to known protein sequences, allowing researchers to determine which proteins are present and in what amounts. This approach enables rapid, comprehensive profiling of proteins, helping to understand biological processes, disease mechanisms, and discover potential biomarkers or targets for therapies.