Serpina1

Serpina1 is a gene that produces a protein called alpha-1 antitrypsin, which helps protect the lungs and liver by preventing damage from certain enzymes that break down proteins. When Serpina1 has mutations or is dysfunctional, alpha-1 antitrypsin levels can be low, increasing the risk of lung diseases like emphysema and liver conditions. It is inherited, meaning it can be passed down through families, and testing for mutations in this gene helps diagnose related health issues. In essence, Serpina1 plays a critical role in safeguarding tissues from enzyme-related damage.