serotonin (5-HT3) antagonists

Serotonin (5-HT3) antagonists are medications that block the action of serotonin at specific receptor sites, primarily in the gut and brain. They are commonly used to prevent nausea and vomiting caused by chemotherapy, radiation, or surgery. By inhibiting serotonin's effects, these drugs help stabilize the signals that trigger nausea, improving patient comfort. Examples include ondansetron and granisetron. They are generally well-tolerated and effective for controlling nausea without affecting other serotonin functions related to mood or behavior.