SERMs in cancer therapy

SERMs, or Selective Estrogen Receptor Modulators, are drugs used in cancer treatment that target estrogen receptors, specifically in cancers like breast cancer. They work by blocking estrogen from binding to these receptors, which can slow or stop the growth of estrogen-dependent tumors. Some SERMs act as antagonists in breast tissue, reducing cancer growth, while acting as agonists in other tissues, like bones. This selective action helps treat or prevent hormone-sensitive cancers while minimizing side effects elsewhere. Overall, SERMs offer a targeted approach, harnessing hormonal pathways to combat specific types of cancer effectively.