SERCA2

SERCA2 (Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2) is a protein in cells that helps regulate calcium levels inside the cell's internal storage (the sarcoplasmic or endoplasmic reticulum). It functions like a pump, using energy to move calcium from the cell's interior back into storage after a cell activity, such as muscle contraction. Proper functioning of SERCA2 is essential for muscle health, heart rhythm, and overall cell function. When SERCA2 activity is disrupted, it can contribute to diseases like heart failure or certain muscle disorders by impairing calcium balance.