Sepsis-3 Guidelines

The Sepsis-3 guidelines define sepsis as a life-threatening response to an infection that causes organ dysfunction, meaning the body's organs start to fail. It emphasizes the use of the Sequential (Sepsis-related) Organ Failure Assessment (SOFA) score to identify organ problems, and considers a significant increase in this score as an indication of sepsis. The guidelines focus on early recognition and treatment, including antibiotics and fluids, to prevent deterioration. They aim to improve diagnosis accuracy and patient outcomes by recognizing sepsis as a distinct clinical condition requiring prompt intervention.