γ-secretase modulation

γ-Secretase modulation involves adjusting the activity of an enzyme called γ-secretase, which plays a key role in processing proteins involved in brain function, especially in Alzheimer’s disease. This enzyme cuts larger protein fragments into smaller pieces, some of which can form harmful plaques associated with dementia. Modulating γ-secretase aims to alter its activity to reduce the production of these harmful fragments without entirely blocking the enzyme, preserving its other important functions. This targeted approach offers a potential way to slow or prevent disease progression while minimizing side effects.